ACE 031

Product Details: ACE-031 (Peptide)

ACE 031 as a peptide is a strong myostatin inhibitor. It has a high affinity to bind to myostatin (GDF-8). It thereby prevents myostatin from binding and activating its natural ACVR2B receptor.  It is studied in experimental and preclinical models as a ligand trap for myostatin (growth differentiation factor-8, GDF-8). Myostatin is a regulatory protein involved in skeletal muscle signaling pathways.

In laboratory settings, ACE-031 is of great interest for checking mechanisms of myostatin inhibition and its downstream effects on muscle-related signaling processes. Its fusion protein structure helps high-affinity binding to circulating ligands within the transforming growth factor-beta (TGF-β) superfamily. This makes it a valuable tool for studying regulatory pathways that are linked with muscle growth and protein synthesis in controlled experimental systems.

Mechanism of Action

In preclinical and experimental environments, ACE-031 functions by binding to myostatin and related ligands, preventing their interaction with endogenous ACVR2B receptors. This sequestration inhibits receptor-mediated activation of intracellular signaling pathways that regulate myogenesis.

By blocking these signaling cascades, ACE-031 is used in laboratory research to examine the upregulation of protein synthesis pathways and skeletal muscle fiber hypertrophy in model systems. Its mechanism also allows researchers to study ligand-receptor interactions, signal transduction inhibition, and regulatory feedback mechanisms within TGF-β signaling networks.

Properties of ACE-031 (Peptide):

• Molecular Formula: C33H57N11O9
• Molecular Weight: 1311.45 g/mol
• CAS Number: 616204-22-9
• PubChem CID: Not Available
• Synonyms: ACE-031; Myostatin Inhibitory Peptide 7; UNII-U8DGS69FVC; CHEMBL3410227
• Peptide Class: Recombinant fusion protein (ACVR2B analog)
• IUPAC Name: UNII-U8DGS69FVC, U8DGS69FVC, 1621169-52-5, CHEMBL3410227, Myostatin inhibitory peptide 7, BDBM50071379, ACE-031, Myostatin inhibitory peptide 7 Ala-Trp-Arg-Gln-Asn-Thr-Arg-Tyr-Ser-Arg-Ile-Glu-Ala-Ile-Lys-Ile-Gln-Ile-Leu-Ser-Kys-Leu-Arg-Leu-NH2

Research Applications/Benefits of ACE-031 (Peptide)

Myostatin Pathway Research

ACE-031 is widely used in laboratory studies to investigate myostatin signaling pathways and their role in regulating skeletal muscle development in experimental models.

TGF-β Signaling Studies

Applied in preclinical systems to examine ligand-receptor interactions within the transforming growth factor-beta superfamily and associated intracellular signaling cascades.

Fiber Tissue Modeling in Experimental Systems

Utilized in controlled environments to study protein synthesis signaling, muscle fiber hypertrophy, and regulatory mechanisms governing myogenesis.

Ligand Trap Mechanism Research

Serves as a model compound for analyzing soluble receptor constructs and their ability to sequester circulating ligands in biochemical and cellular studies.

Protein Engineering and Biologics Research

Used in experimental settings to explore recombinant protein design, stability, and binding affinity in advanced molecular research applications.

Why Choose BehemothLabz to Buy ACE-031 (Peptide)

BehemothLabz is committed to providing high-purity research compounds manufactured under strict quality control standards. Each batch of ACE-031 undergoes independent third-party testing to verify identity, purity, and consistency. With a focus on scientific reliability and transparency, BehemothLabz supports researchers with dependable compounds suitable for advanced laboratory and preclinical investigations.

Disclaimer: This information is for educational purposes. We do not allow the human consumption of our products. All our products are sold for laboratory and research experiments.

ATTENTION: All BehemothLabz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human or veterinary purposes.