YK-11 (Myostine) is an investigational synthetic steroidal compound classified within the selective androgen receptor modulator (SARM) research category. It is supplied for laboratory-based research and intended for use in controlled experimental environments.
In preclinical and in vitro models, YK11 capsules are examined for their interaction with androgen receptor (AR) signaling pathways. Structurally derived from dihydrotestosterone (DHT), it exhibits partial agonistic activity at the androgen receptor in experimental systems. This distinguishes it from classical full agonists.
Mechanism of Action
In vitro studies indicate that YK-11 binds to the androgen receptor and functions as a partial agonist, leading to selective modulation of downstream transcriptional activity.
Experimental findings suggest that YK-11 influences the expression of follistatin, a regulatory protein associated with the transforming growth factor-beta (TGF-β) signaling network. This includes pathways related to myostatin. [1]
At the cellular level, YK-11 has been observed to:
- Modulate androgen receptor-mediated gene transcription. [3]
- Influence follistatin expression in myoblast-derived cell lines. [1]
- Affect signaling pathways involved in cellular differentiation and protein regulation. [1][2]
These observations are derived from controlled in vitro systems and remain under investigation in broader experimental models.
Properties YK-11 (Myostine) Capsules:
- Molecular Formula: C₂₅H₃₄O₆
- Molecular Weight: 430.5 g/mol
- CAS Number: 1370003‑76‑1
- PubChem CID: 119058028
- Synonyms: YK-11 / Myostine
Research Applications/Benefits of YK-11 (Myostine) Capsules
YK-11 is utilized in research settings to investigate:
- Selective modulation of androgen receptor activity in in vitro systems. [1]
- Structure–activity relationships (SAR) of steroidal SARM analogs. [2]
- Regulation of follistatin expression in cellular research models. [1]
- Interactions between androgen signaling and TGF-β-associated pathways. [1]
- Mechanisms of receptor-selective transcriptional regulation. [3]
These applications are limited to laboratory and preclinical research and do not indicate clinical or therapeutic use.
YK-11 Injectable vs Capsules: Choosing the Right Research Format
Researchers working with YK-11 Injectable typically choose between two supplied formats — capsules and injectable (parenteral) solution. Both formats deliver the same underlying compound (C₂₅H₃₄O₆, CAS 1370003-76-1), but they differ in formulation, solvent carrier, and the type of experimental model they are best suited for.
YK-11 Capsules
YK-11 capsules encapsulate a fixed quantity of the compound in a solid oral-research format. This form is commonly selected for:
- Studies requiring a stable, room-temperature-storable research format
- Experimental protocols modeling oral-route absorption and metabolism
- Simplified handling and measurement in bench-scale research setups
YK-11 Injectable (Parenteral Solution)
The injectable format suspends YK-11 in a solvent-based carrier, supplied as a liquid research solution. This form is generally used for:
- In vitro and in vivo models requiring direct compound delivery, bypassing first-pass metabolic pathways
- Research into receptor-binding kinetics where oral absorption variables need to be excluded
- Studies where precise volumetric dosing at the bench level is required
Why choose BehemothLabz to buy YK11?
Choose Behemoth Labz, choose quality! We are among the few online sellers that believe in the integrity and purity of products. We offer YK-11 for sale, which is designed to meet the industrial criteria and the needs of researchers.
Before launching our products, we test them through an independent laboratory to check their purity and ingredients. This procedure maximizes the accuracy and findings of your research experiments.
Additionally, we deliver nationwide and internationally. We use a secure payment system that safeguards your personal information and prevents unauthorized third-party access.
So, purchase YK-11 (Myostine) now and experience quality and purity for your research.
Disclaimer: This information is for educational purposes. We do not allow the human consumption of our products. All our products are sold for laboratory and research experiments.
References:
- Kanno, Y., Ota, R., Someya, K., Kusakabe, T., Kato, K., & Inouye, Y. (2013). Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression. Biological and Pharmaceutical Bulletin, 36(9), 1460–1465.
- Yatsu, T., Kusakabe, T., Kato, K., Inouye, Y., Nemoto, K., & Kanno, Y. (2018). Selective androgen Receptor modulator, YK11, Up-Regulates osteoblastic proliferation and differentiation in MC3T3-E1 cells. Biological and Pharmaceutical Bulletin, 41(3), 394–398.
- Kanno, Y., Saito, N., Saito, R., Kosuge, T., Shizu, R., Yatsu, T., Hosaka, T., Nemoto, K., Kato, K., & Yoshinari, K. (2022). Differential DNA-binding and cofactor recruitment are possible determinants of the synthetic steroid YK11-dependent gene expression by androgen receptor in breast cancer MDA-MB 453 cells. Experimental Cell Research, 419(2), 113333.

