DNSP-11

Buy DNSP-11

Buy DNSP-11 from behemothlabz for laboratory research. Review the exact product identity and listed format before choosing this material for your work.

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Listed strength options:

• 10mg
• 5mg

Select the exact option to see its current price and availability. Quantities and concentrations describe the listing and are not use instructions.

Mechanism of Action

Experimental studies indicate that DNSP-11 exhibits biological activity in dopaminergic neuron models that differs from full-length GDNF. The observed effects do not fully align with classical GDNF receptor signaling, indicating the potential involvement of alternative or intracellular-associated mechanisms. [1][3]

In vitro findings show that DNSP-11 can influence cellular processes associated with neuronal maintenance under stress conditions. These observations support its use as a research tool for investigating peptide-mediated signaling pathways in dopaminergic systems. [1]

Properties of DNSP-11:

• Molecular Formula: C₅₀H₈₁N₁₅O₁₈·xC₂HF₃O₂ (TFA salt)
• Molecular Weight: 1180.27 g/mol (C₅₀H₈₁N₁₅O₁₈)
• CAS Number: N/A
• PubChem CID: 25168985 for DNSP-11
• Synonyms: Dopamine Neuron Stimulating Peptide-11, GDNF Propeptide Fragment

Dopaminergic Neuron Function Studies

DNSP-11 is used in experimental models to investigate signaling processes in dopaminergic neurons. These neurons are widely studied due to their role in neurological conditions characterized by dopamine system dysfunction. [1][4]

• Neurodegeneration and Oxidative Stress Models

Dopaminergic neurons are particularly sensitive to oxidative stress, which contributes to neurodegenerative processes. DNSP-11 is applied in laboratory models to examine cellular responses under these conditions and to explore peptide-associated effects in stressed neuronal systems. [4][5]

• Intracellular Peptide Signaling Research

DNSP-11 provides a model for studying peptide fragments derived from neurotrophic factors and their potential activity beyond classical receptor-mediated pathways. This supports investigation into alternative signaling mechanisms within neuronal cells. [1][3]

References

1. Bradley, L. H., Fuqua, J., Richardson, A., et al. (2010). Dopamine neuron stimulating actions of a GDNF propeptide. PLoS ONE, 5(3), e9752.
2. Lin, L.-F. H., Doherty, D. H., Lile, J. D., Bektesh, S., & Collins, F. (1993). GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science.
3. Airaksinen, M. S., & Saarma, M. (2002). The GDNF family: signalling, biological functions and therapeutic value. Nature Reviews Neuroscience.
4. Dauer, W., & Przedborski, S. (2003). Parkinson’s disease: mechanisms and models. Neuron.
5. Gandhi, S., & Abramov, A. Y. (2012). Mechanism of oxidative stress in neurodegeneration. Oxidative Medicine and Cellular Longevity. 

Documentation for laboratory purchasing

For batch-dependent specifications, request the report associated with the material you will receive. Match the product identity, lot number and test date to your records. Review the relevant safety data and laboratory requirements before handling the material.

Ordering questions

Which DNSP-11 option should I select?

Choose the exact listed quantity or configuration required by your laboratory. For blends, confirm the amount of each component rather than assuming the total is a per-component amount.

What documentation should I check?

Check the batch identity and the analytical evidence relevant to your requirements. A general product description does not replace a report for the supplied lot.

Is this intended for personal use?

No. This product is offered for laboratory research only and is not for human or veterinary use.

Related research products

• Pinealon
• DSIP (Delta Sleep Inducing Peptide)

These links are provided for catalog comparison. They are not recommendations to combine or administer products.

Browse the Peptides category for more listings.

For laboratory research only. Not for human or veterinary use.