Product Details: Gonadorelin Peptide
Gonadorelin is a lab-made decapeptide. It is structurally identical to endogenous gonadotropin-releasing hormone (GnRH). It is a key regulatory peptide produced in the hypothalamus. As a member of the GnRH peptide class, Gonadorelin is of great interest in laboratory and experimental settings. It is used to study endocrine signaling pathways. This is done within the hypothalamic-pituitary-gonadal (HPG) axis in particular. Its precise structural mimicry of natural GnRH makes it a valuable tool for:
- investigating hormonal regulation
- receptor binding dynamics, and
- feedback mechanisms in controlled research environments
Mechanism of Action
Gonadorelin places its effects by binding to GnRH receptors. These receptors are located on cells of the anterior pituitary in experimental models. This interaction stimulates receptor-mediated signaling pathways. The stimulation results in the controlled release of gonadotropins, specifically luteinizing hormone (LH) and follicle-stimulating hormone (FSH). The peptide works in a pulsatile manner in laboratory studies. This is very important for maintaining receptor responsiveness and studying endocrine feedback loops. Due to its rapid degradation and short half-life, Gonadorelin is very useful in experimental systems designed to assess temporal hormone signaling and regulatory dynamics.
Properties of Gonadorelin Peptide:
- Molecular Formula: C55H75N17O13
- Molecular Weight: 1182.3 g/mol
- CAS Number: 9034-40-6
- PubChem CID: 5311128
- Synonyms: Gonadorelin, Luliberin, Gonadorelina, Gonadorelinum, LH-Releasing Factor, Luteostimulin
- Peptide Length: 10 amino acids (decapeptide)
- IUPAC Name: (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Research Applications/Benefits of Gonadorelin Peptide
Endocrine Axis Research
Gonadorelin is used a lot in laboratory models. It is done to investigate the regulation and signaling dynamics of the hypothalamic-pituitary-gonadal (HPG) axis. It gives insight into hormonal communication pathways.
Receptor Binding Studies
The peptide serves as a model compound for analyzing GnRH receptor interactions. The interactions include binding affinity, receptor activation, and downstream intracellular signaling in experimental systems.
Hormonal Feedback Mechanisms
Gonadorelin is applied in preclinical research to study feedback loops and pulsatile hormone release patterns. This enables detailed examination of endocrine regulation in controlled environments.
Pituitary Function Analysis
In experimental settings, Gonadorelin is used to check pituitary responsiveness and signaling output. This is particularly in relation to gonadotropin secretion dynamics.
Peptide Stability and Kinetics Research
Due to its short half-life, Gonadorelin is valuable for studying peptide degradation, metabolic stability, and temporal signaling behavior in laboratory conditions.
Why Choose BehemothLabz to Buy Gonadorelin Peptide
BehemothLabz is dedicated to delivering high-purity research peptides produced under stringent quality control standards. Each batch of Gonadorelin peptide is manufactured in controlled environments and undergoes comprehensive third-party testing to verify identity, purity, and consistency. With a focus on reliability and scientific integrity, BehemothLabz provides researchers with dependable compounds suitable for advanced laboratory and experimental applications.
Disclaimer: This information is for educational purposes. We do not allow the human consumption of our products. All our products are sold for laboratory and research experiments.
ATTENTION: All BehemothLabz products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human or veterinary purposes.
References:
- Conn PM, Crowley WF Jr. “Gonadotropin-releasing hormone and its analogs.” Annual Review of Medicine. 1994;45:391–405. https://doi.org/10.1146/annurev.med.45.1.391
- Millar RP, Pawson AJ, Morgan K, Rissman EF, Lu ZL. “Diversity of actions of GnRHs mediated by ligand-induced selective signaling.” Frontiers in Neuroendocrinology. 2008;29(1):17–35. https://doi.org/10.1016/j.yfrne.2007.07.002
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