SR-9011 Liquid

SR-9011 is a synthetic small-molecule compound classified as a Rev-Erbα agonist. This compound is utilized in biochemical and molecular research to study the interaction of small molecules with nuclear receptor proteins, specifically the Rev-Erbα receptor, which belongs to the nuclear receptor superfamily.

SR-9011 is relevant in laboratory studies investigating receptor-ligand binding, transcriptional regulation, and downstream signal transduction pathways associated with nuclear receptor activation.

Mechanism of Action

SR-9011 interacts with the Rev-Erbα nuclear receptor at the molecular level. Binding of SR-9011 to Rev-Erbα stabilizes the receptor-ligand complex, facilitating recruitment of co-regulatory proteins and modulation of transcriptional activity.

This mechanism is investigated in vitro and in controlled biochemical systems to examine the compound’s effects on transcriptional regulation, ligand affinity, and receptor-mediated signaling dynamics. Studies focus on molecular interactions, receptor conformational changes, and pathway activation patterns without referring to physiological outcomes in living organisms.

Chemical Properties of SR-9011

Research Applications

Nuclear Receptor Binding Studies

SR-9011 is used in laboratory research to study ligand interaction with Rev-Erbα receptors. Investigations include receptor binding affinity, complex formation, and co-regulator recruitment.

Transcriptional Regulation Research

The compound is applied in studies analyzing nuclear receptor-mediated transcription. Research focuses on pathway activation, modulation of transcriptional activity, and mechanistic understanding of receptor-ligand interactions.

Structure-Activity Relationship (SAR) Analysis

SR-9011 is relevant in structure-activity studies to examine how modifications in the small molecule influence receptor engagement, binding kinetics, and downstream molecular signaling.

Biochemical Signaling Pathway Investigation

The compound is used in studies assessing molecular signaling cascades activated via Rev-Erbα interactions in controlled in vitro and cell-based assays.

Note: SR-9011 is for sale for research purposes. It is not approved by the FDA for medical use.

Why Choose Behemoth Labz to Buy SR-9011 for Research

Behemoth Labz provides SR-9011 liquid for sale that is manufactured under controlled laboratory conditions with strict quality assurance protocols. Each batch undergoes analytical verification to ensure consistency in molecular composition and purity.

Comprehensive documentation, including laboratory testing reports and sourcing transparency, supports reproducibility in experimental settings. BehemothLabz maintains a compliance-focused approach, supplying compounds intended strictly for laboratory-based investigation and analytical research

Disclaimer

SR-9011 is intended strictly for laboratory research and analytical purposes only. It is not intended for use in diagnostic procedures, therapeutic applications, or in vivo studies of any kind.

Any references to biochemical pathways, receptor interactions, or enzymatic processes are provided solely for informational and research-context purposes. This compound must be handled exclusively by qualified professionals in controlled laboratory environments in accordance with applicable regulations and safety guidelines.

Improper handling or use outside of controlled research settings is strictly prohibited.

References

• Shin, Y., Noel, R., Banerjee, S., Kojetin, D., Song, X., He, Y., Lin, L., Cameron, M. D., Burris, T. P., & Kamenecka, T. M. (2012). Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα. Bioorganic & medicinal chemistry letters, 22(13), 4413–4417. https://doi.org/10.1016/j.bmcl.2012.04.126 
• National Center for Biotechnology Information (2026). PubChem Compound Summary for CID 57394021. Retrieved March 18, 2026 from https://pubchem.ncbi.nlm.nih.gov/compound/sr9011